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Materials and methods: Hcy levels were determined by ELISA, and Se levels were determined by atomic absorption from serum samples isolated from peripheral blood of 56 colorectal cancer cases and 87 healthy controls. The expression of SELENBP1 gene in tumor samples was determined by RT-PCR method. Similarly, selenium (Se) levels and SELENBP1, a member of the selenoprotein family characterized by selenium, have is there any casino in istanbul been evaluated for the etiopathology of colorectal cancer (CRC). Results: Se levels were 67.56 +/- 3.11 ng/mL in colorectal cancer patients and 61.92 +/- 21.26 ng/mL in control group patients (p = 0.078). Serum Hcy levels were 11.34 +/- 1.75 ng/mL in the patient group and 20.87 +/- 4.38 in the control group (p = 0.340). The SELENBP1 fold change was found to be 3.78 +/- 1.95-fold higher in tumor tissues compared to internal control (p = 0.755). Se levels were found to be 1.23 times lower in patients with distant metastasis than in patients without distant metastasis (p = 0.029). Similarly, Hcy level was found to be 1.79 times lower in patients with metastasis than in non-metastatic patients (p = 0.035). Conclusion: Our data suggest that low Se and Hcy levels may play an important role in the histopathological aspects of metastatic ability and CRC. Is there any casino in istanbul. T.C. İÇİŞLERİ BAKANLIĞI. WEB SİTESİ GİZLİLİK VE ÇEREZ POLİTİKASI. T.C. Rüyada koyun sürüsü there görmek , geneli itibari ile iki farklı anlam barındıran bu rüya, itaat etmeye ve şans açıklığına işaret eder.