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Şiddetli durumlarda Faktör X ve protrombin replasmanı da yapılır Von Willebrand hastalığı Von Willebrand faktörü (FvW) eksikliği ile ortaya çıkar. İnsanlarda en sık görülen kalıtsal kanama hastalığıdır. 9 Bazı yayınlarda %1 2 arasında olduğu belirtilmekle beraber orta ve ileri derecde kanama riski gösteren gerçek klinik vakalar için bu oranın düşük olacağı düşünülebilir. 10,11 FvW pıhtı tıkacı ve fibrin oluşumunda yer aldığı için ileri derece eksikliğinde kompleks kanama problemleri ortaya çıkar. Uzamış kanama zamanı ile beraber faktör VIII seviyesinin düşüklüğüyle karakterizedir. 1 Sıklıkla dişeti ve mukoza kanamaları görülürken eklem içi kanamalar ileri durumu olan hastalarda görülür. Türünün dördü için ödül 50 jetondur ve kişisel hesapta vavada kaydı türünün üçü için 10 jeton kazanırsınız, özellikle 4D piyangoda yeniyseniz. Hafif durumlarda dezmopresin takviyesi yeterli olurken ağır durumlarda ek olarak faktör VIII takviyesi düşünülür. …

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